A 52-year-old female patient presented a failure of 6 implants supporting a fixed bridge, after 6 years after their placement. The failing implants were removed and all the zygomatic implants were inserted at the level of the zygomatic bone and allocated in the maxillary bone.

A male patient had advanced cancer of the face/sinus, for which he received life-saving surgery with loss of his left eye, cheek, and jawbone and much of his skull. He could not have a surgical reconstruction due to his medical history.

A 68-year-old female patient suffered from tooth loss and removable dentures for more than 20 years.  A protocol considering four zygomatic implants was chosen to avoid lengthy and invasive bone grafting procedures.

A 62-year-old male presented with tooth #16 FDI (#3 US). Despite the lack of bone volume posteriorly, he had sufficient volume anteriorly and an abundant amount of keratinized tissue making him a good candidate for an All-on-4® treatment concept with a hybrid restoration.